GHRP6 (Growth Hormone Releasing Hexapeptide) is a peptide hormone of the Growth Hormone (GH) class. The purpose of GHRP6 as is, with all related peptides, to increase the amount of natural GH production in the body. Increases in GH can be beneficial to anabolism, fat loss, recovery and general well being as well as serve possible anti-aging purposes.
GHRP6, and this applies to all GHRP hormones, mimic the production of ghrelin. This mode of action stimulates the ghrelin receptors, GHS-R1a or Growth Hormone Secretagogue. This stimulation acts to increase GH production by stimulating the pituitary, specifically the ghrelin receptors located in the pituitary.
When the body is in a fasted state, this is when ghrelin levels are elevated. When the fasted state is met by elevated ghrelin activity, the resulting stimulation can lead to a greater production of GH in the body. However, the increase in ghrelin does not end with increases in GH. Elevated ghrelin is also known to stimulate the appetite, which may be useful for those who need excess calories to grow yet find eating difficult. Alternatively, the hormone will promote fat loss and more importantly enhance the rate of recovery.
However, while ghrelin has been shown to promote recovery, in cases of GHRP6 and elevated GH levels it is more likely that the corresponding elevated levels of IGF-1 play a larger role. IGF-1 levels will not spike at the rate comparable to direct Human Growth Hormone (HGH) use as the pulsating effect of GHRP6 is short-lived.
GHRP6 is also a hormone that is dependent on glucose, specifically when blood sugar levels are low. Elevated levels of blood sugar will render GHRP-6 weaker, meaning it must be taken during a fasted state for any intended benefit to be had.